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    impairedCMPA results from an immunological reaction to one or more milk
    proteins.2 This immunological basis distinguishes CMP allergy from
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    infants with a mean age of7 months (range 2 11 months) with CMPA
    diagnosed by means of double blind, placebo controlled challenge, 58%
    showed an earlyreaction within 2 h after the last challenge dose. These
    early reactions usually manifest as urticaria, angio oedema, vomitingor
    an acute flare of atopic dermatitis.

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    We did not analyse efficacy data for ondansetron as prophylaxis
    against postoperative nausea and vomiting. Reports that were described
    as randomised were given one point, plus a further point if the method
    of randomisation was described and adequate (such as a table of random
    numbers). There had been an earlier agreement that trials without
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    concealment of treatment allocation) would be excluded from further

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